Jan 10, 2018 If you have an allergic reaction to an insect sting, there are a few options for treatment. They can help reduce swelling, itching, and hives. (Chlor-Trimeton); dimenhydrinate (Dramamine); diphenhydramine (Benadryl, Sominex); doxylamine (Vicks Nyquil) . What to Do for Yellow Jacket...