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Can Accutane cause birth defects years after taking it? Accutane, also known as isotretinoin, is known to cause birth defects, including brain, heart, and face deformities, if women take it while pregnant. Because of this, it is recommended that women of childbearing age taking the drug be tested for pregnancy before starting it and then repeatedly during their treatment.
Does isotretinoin have long term side effects? Xeroderma, dry eye syndrome, arthralgia, and possible exacerbation of eczema, were considered to be infrequent but probable long - term side - effects. The findings of this study indicate that isotretinoin in the treatment of acne is a safe drug, with no serious long - term side - effects.
What is the half life of Accutane? After a single, 80 mg oral dose of Isotretinoin to 74 healthy adult subjects under fed conditions, the mean В±SD elimination half-life (t 1 / 2) of isotretinoin and 4-oxo-isotretinoin were 21.0 В± 8.2 hours and 24.0 В± 5.3 hours, respectively.
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